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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef6fba3a36458f1faf53816ef2824e376db367a7fbc703847c950c92c8a1a7ff' 
  AND token = 'JBA3CEBPPM74vi4LHB/Sq9D95momWjIqQ7GJi21iUro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}