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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bc9d2753a82c68c36b7f1fc9bfedeee77a48881ee40d437bec6faff1ea661cb' 
  AND token = 'iLeoakxraBAOkCWJYzubloKYSw7wZqXQ4VZ3wYSn1IM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}