SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9483c7c8d637e92b5ed09a9441fa3afb5e8bc8a256faacdec7b4627002a09e9' 
  AND token = 'QVJlNoEXic7UPKgW3SOFNbVG7PjHQlHNDRfwiGWSo2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}