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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67292924a7d4e88e8eac7dccdd90e9fa8747937fff8da72af236633e9af9a51b' 
  AND token = 'RBDy58u4EzUv+mHMwa+IuyHS22/AWn2C/mGQkLDeGHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}