SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '328a74135c93c07b380a2833063f15395e43bbbe13e04a4f33bba97bcd9c0105' 
  AND token = 'Ppy0+h/ajiBX2lJKJBLzrpKMhSu05LyS7pEc36rngKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}