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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '649452bd8e952658f3bcb90300100b72bb800040aed01502af2929747c6cdfb3' 
  AND token = 'lRnrkZZyrv1vpiO0X/MDvVyLYZBPsoxyPw4BTmAF40k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}