SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6241c0513a476fa33a93a951aee2f1760bb7702c22403a8fe66efca919fd440' 
  AND token = 'PNCqrrfqLvh8WgKyHjYPFWcrmE7N9c1JAOiCBF8yMDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}