SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd03dc21a2a6ccf8b5c5feb1cab8434b3fd33fd4cd0b9ca4c5368a4dfd45356c4' 
  AND token = 'F8n6Ms8CiezOdfd7y0yz9uzyikQYaPu8qEwz02gNfzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}