SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b48ef20984c1ef3e5b64db0400efcc9c364a1881bb9165f7bfa882e6152d9ef0' 
  AND token = 'MByn8w5KKBl67W0OksfbT+bsqpUkWFXGqJUSYw41l8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}