SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27464a3dc5d1475ed5282ab78af94cb000b84c11d38407003ae52357b6c8f0b3' 
  AND token = 'T5R2XJOklt0o1xTXNQZ9MJtryU4G/Nm3MK/RRKZzBYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}