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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45196ba3c3eb742223fa1442c51391d292d6e634051edc6b54691e20766af36a' 
  AND token = 'Ube3fqkTC/HDgLv5qGzAl9PVAEEA5LNDmSQnxRCXBIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}