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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57d930779bde83ab518eebbf5cbde13981eeaeb8fb781633b1769a6458c7a02b' 
  AND token = 'z+0IH4SzagNPzSw0mFaIfMsmub2/IogMbliC/YUdeF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}