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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5265630f24cc12e6e68c54d7d3c7aa3fe61ca28c7575269336fa4b5c3f48be19' 
  AND token = '1I4w6tMQpOOH9FRVm9MDlNpzE1sDHPqKsb7nINs9r/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}