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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72ff06c55cda3e0399cff458e49578a46a65ee36d8a9f51ad7ce7511cc992642' 
  AND token = 'abLs3RBAZDlfK0oB4L+hVz7CgtcM59os9QUVuQDmkds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}