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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b3b5f207406048d2c8111367ae887682bfa8f5d0a209f2cb1ada3228b76bc6b' 
  AND token = 'Ykpgf+GrSD9seX+aTGxS/JMCHos3sEpA1oJUR4anyzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}