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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c587a87f81f43d534a2495b78e6b75bd4460e516d282856519f86a3dc8cfb283' 
  AND token = '4hGpFM9IMr47G8TkhrrsiH4GMOI6nl/uOiTP0HjiVDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}