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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '816eb0b00446ba5ca593a23c42dd362e9d1145924c75a1fe4da29e54e8b469ac' 
  AND token = 'tLE4zFMhL8x+jBA1gMvrasjqegBpTta1IJkC1UiZMcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}