SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '503ea9911544b6c878156195d6f92fc22c5c6a03d2714c10fc8e674a5a7b2f44' 
  AND token = 'NrKaRWNwKhy4FYwYmY0eW1jq+Q01SaH5LnEDe0sIjuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}