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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8589c614b0c74d1685fde25f1e1c754251c5a097dc6e8e8487d9bf8e87710ddf' 
  AND token = 'E03y3CSxG2KwfD2dNmBWU5HxTVEUTa0SArSklbyOtys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}