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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f458f1ea943afe536882ff0c1b151270874d5baa2fbbff32057afc127ab4bbbd' 
  AND token = 'x4ekS7XFEJ1u1nkvV7X5iFG4xYk/8I9Vxt1eCAs1wPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}