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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d74ac565bc80e9bfe7f8ea6c6e960a5c23da8f95e3f48786ba45edea290b7a7' 
  AND token = '3Ox5I0qirjT4accawNk0PAvsVoI7R7zTbpfrdEFDNh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}