SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '657bea9cceab039d09fad506ae8a5f8934465f10f6e62d388ce9d48a2abbe0c6' 
  AND token = 'eRyFq2v7QX8WirOMNVlsftSGwTpTLdArPSKNd9mxYaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}