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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22afaa1bae922970012f38752446e3fccb7352d624591f4466a8d944d4e956fb' 
  AND token = 'xl4+VOXN0jQ5/iPqIsHFlySMOaPI1zWFel8BOVRfZ98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}