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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45efc6dd4ae5bd3111654a4d7dc254b78d46393ff7ed9e746c010595aa4066ce' 
  AND token = 'gpT2QQoltXYwxoABEfJeh+3+4nm5hWgGpfJAFs0tLhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}