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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b39e444e84ac30d4ce4d1b995c12fd8e506a4eb4901b5ae807141b5c8b453b34' 
  AND token = '2sMhzEo08wCJzrZE7tzzC+BxBDUXeYRlSJG+JdNZCAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}