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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adb11986fad624e68376313840150403b8694faa84a417a4ab159cc98d616aef' 
  AND token = 'BDCgnXmgFjey8hNIf2mpoXZ9/fBg+34Qz0ZedhmgeEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}