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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48e578de30c8b60ad4d1f3fa4be843b43114cdaba79905521dd376262f9eaead' 
  AND token = 'wNcpJTL93+pWuUZTk8+vSNPAjMFjZt4i7ABc+4anbs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}