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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5175c18515215d828272d7c1fbf99c261c1e2ec2a45bac2951bc3acada1f075e' 
  AND token = '8MBWTB9TDZMIq6L715CUVrgOC5n9eJ4MhSe9ue/8QMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}