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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d3ba3cec903eaeba79ae276363ef3a9ec040cb158ff74b0397a4a217b23b256' 
  AND token = 'Zmme3DD40Vc4SUhFS++2pFaIDZjPCcfXIQ2imOQuxBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}