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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f0f6cd6ca0834f4bc99f11a048d32c6d339c5c337b3e4d1cc41036dd527ca12' 
  AND token = 'hN2h0Q+ESfs9sPkmqb2CBz+UItGsJ4v78MBdi5CiCH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}