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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3ff8a0a350a0e0ce6e5da38f5574bd3e57bbce61f494d6aa2c5d46919854300' 
  AND token = 'ZRI+F1ulPa6Bo3EbkDMy3a0sSgAvSJ9Qb3XWm5tNCW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}