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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e166f4e640730b690fcadfc9c1d968ac4d776a9a2913dfb94450b2da0b02d07e' 
  AND token = 'zGtE2lCXFuyCgJolAl//ZEzQT28S4lmQlsQccb0vQt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}