SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80ad02b8b48b392665072181978f27b22f9b0e1e1e4cf7064cd213351dbf8b1f' 
  AND token = 'f6tx4hVYZyNP71vRjPNt/elxRUJ1HRDnnseMGFECsjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}