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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49c3510d099ddccca79ba5fd960a3134d030a0acc6d26d757e675bce5e685ad0' 
  AND token = 'SdBbKJS91h4Rq+nojL3OTGkPMYuRxj00oEu3lq7xZ6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}