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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c3d7d5c6a09bff36b180e5d829e0bf8aac8bb603a1382e3bffe81cf3757477a' 
  AND token = '18cpPX5i+aNT9tV5H+86PmwaH6wIv+s3+cyg5QpYihM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}