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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27508f6480bdb039f7e88b2190c97dc4a46be7fe2d1cfeccdd16e7b196c6f9a3' 
  AND token = 'AoHWnCkVpOshKhmol+J4biqo6kaBHgKjWdHVSblynv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}