SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c142a3c70b953fc25c342f611a6b51dcef210881528c03b3783bb4419e22e3b' 
  AND token = 't05koyS8dL9MgTRygJByiGHLnK+abL1z0hpJZXr7/e0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}