SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03cf1886313752c9b42cbdc13b2eb740c9267143da2221c1c851c79275eb9cf9' 
  AND token = 'HnTknx5k+mOIbzdbA9JPl5mykT0KiPfFjuog4Hm+FJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}