SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64fe0ccd218d7adf88e265b8d415a8bdb6ae4b775271e290525f6b5cdaddae21' 
  AND token = 'Lw15asqx5XuIjXtXo30K4TSOm8HA/8r4T1qq55hWn+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}