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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73e5a78d80071c5feef0c6da80588ba1b005e94da5d0d8e134f03a554f2692fc' 
  AND token = 'fR3O8nodDNWtuITl5dYlS5ywyGoSh9pCwLVVHLu8IHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}