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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '818bbf3c1399c858976b68737f2ad4ecad6283e890090cc622584db4cd8ea02e' 
  AND token = 'sZg4MvekIx5PaUfFh5RCV9FaafV+fMQlm469dVSnejM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}