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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70553671a9f410ee8ce7749ae9d1a333af0d1976e9cf24d64a193dbc589eb448' 
  AND token = '68FUfruh0BM8holh5IoFTaFT2wewlJh0bFOuMrSHym0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}