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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1f7e1a5d3207416fade1d164003c56693b2f0a629d25dd72d0d15f213cab1ec' 
  AND token = 'RPlJq0nNgHsTJWRuUo7NaZmZDp8V14c4D2Rt+xodTjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}