SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '182d0e16a1714ec5ede4d615777599a5b426f7dc02f0e38fb2ed20a7e8a6ea87' 
  AND token = 'ua5a5jHZuBQyKgORvS3vcrZAIzFMJEHLPEtWumCUyTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}