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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0329c7b0ee8310fbd626831f4714d2e9a04bb840bb411596c5d4b563ab050085' 
  AND token = 'O5bRMzbB+sXFOx9bcgfe6tTiRSA7q7jna6lTYMaPp20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}