SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46e0d38239f1a73c4f7297562312375f9dd56767780472ad600f0cc0eabbe38b' 
  AND token = 'q2BkmD9UJRfBBgK0ILY46o1w+Ojxp+MvOLPjuGUxyH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}