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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6829ae8cbb4aebf68155be3d690c4c065e2585c9172fea81d8cf4f0089968619' 
  AND token = 'ifb5VEPeZ39CFZ10TsK7RVT+b5Qe3IBXOWavz5iDVLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}