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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa360b0d36d12807128c99b84fe0ba43a0f3a05d3c5b29244325554bd4a5e096' 
  AND token = 'G6wS3jDQlxc05CiWGtY/kTfUAVRuDH6C4MkT4JaTT0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}