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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f6a1d52b459b1a0b1fab4868d9750cc31f55aaea9c70c5a65904e75c24dae99' 
  AND token = 'VS9i7Z+bIA/Jch2xhhOR6+PAlWxKQX2P11sGSiufRGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}