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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68e4646cbed04ca7f3f4b24e0fc5d5f0e7e87a8decebd23a25992e37208f714e' 
  AND token = 'w2sTwoD/3OLaZZEhXkBzMxTrVIhUkLJZASBy0LP46rM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}